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Designed:  The only sealant specially designed for the lung and its unique characteristics Combines Polyethylene Glycol (PEG) and Human Serum Albumin (HSA) to form a flexible hydrogel Gels at the tissue site, binding directly to the lung for optimal adherence and an airtight seal Strong enough to withstand re-expansion of the lung within 2 minutes of application2,3 Highly elastic to allow the lung to expand and contract naturally during respiration The patented Progel™ Spray Tip allows for customized application from a single, easy-to-use device Indicated: The only sealant approved by the FDA to treat pleural air leaks2 Now FDA approved to treat air leaks in open thoracotomy, Video-Assisted and Robotic Assisted Thoracic Surgery2 Clinically Proven:  The only sealant clinically proven to effectively treat air leak complications in both open and minimally invasive thoracic surgery1,2 Sealed or reduced 96% of air leaks in the OR in a recent clinical trial of patients undergoing Video-Assisted or Robotic-Assisted lung resection2 Reduced inpatient length of hospitalization by an average of 1.9 days in a prospective, randomized clinical trial1 Cost Effective:  As many as 58% of lung surgery patients will have an air leak in the OR1, and more than 15% will develop a persistent air leak after surgery4 Identifying and treating air leaks intraoperatively provides the best chance for preventing persistent air leak complications and providing incidental cost-of-care savings5 Progel™ Pleural Air Leak Sealant has been shown to effectively seal air leaks during lung surgery, reducing length of hospitalization by 1.9 days on average, potentially minimizing associated complications and providing cost-of-care savings1         1.  Allen, Mark S. et al, “Prospective Randomized Study Evaluating a Biodegradable Polymeric Sealant for Sealing Intraoperative Air Leaks That Occur During Pulmonary Resection” Annals of Thoracic Surgery 2004; 77:1792-1801. Pivotal study. Data on file. 2.  Progel™ Pleural Air Leak Sealant Instructions for Use. M-00368. Davol Inc. Data on file. 3. Davol Inc. In Vitro Bench Testing. Data on File. In vitro test results may not correlate to clinical performance. 4. Brunelli et al. Predictors of prolonged air leak after pulmonary lobectomy. Ann Thorac Surg 2004; 77: 1205-1210. Based on the reported incidence of prolonged postoperative air leak. 5. Okereke, I, Murthy, SC, Alster, JM, Blackstone, EH, Rice, TW. Characterization and Importance of Air Leak After Lobectomy. Ann Thorac Surg 2005;79:1167-1173. 6. Estimated based on 4Q 2014 sales data and an estimate of 1.2 mL kits per procedure. 

Medical Devices
Medical Diagnostics



Los Angeles






Total funding


Last funding

7 years ago



Growth score


Mindshare score




$20.0M Series D

Aug 3, 2011

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Key People

President and CEO
Key Account Manager
Director Quality Assurance
Associate Director of Advanced Quality Engineering - New Products (BioSurgery)
Operations Manager
R&D Engineer II
R&D Engineer
Manufacturing Supervisor
Manager, Corporate Administration
Account Manager
Area Vice President
Medical Device Sales
Territory Sales Manager
Area Vice President
Account Manager
Thoracic Area Manager
Teritory manager

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